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Friday, 6 June 2014

Harvard Confirms Book Is Bound in Human Skin.

Harvard Confirms Book Is Bound in Human Skin.

"Des destinées de l'ame" by Arsène Houssaye.  

“Des destinées de l’ame” by Arsène Houssaye.

scientists at Harvard have confirmed that a 19th-century French treatise in the university’s libraries is almost surely bound in human skin, thus ending months of uncertainty and setting off a torrent of online Hannibal Lecter (get it?) jokes.

The book, Arsène Houssaye’s “Des destinées de l’ame” (On the Destiny of the Soul), came under renewed attention in April, after researchers concluded that another book at Harvard previously thought to be an example of anthropodermic bibliopegy — as the practice of binding books in human flesh is known — was in fact bound in sheepskin.
The Houssaye book, deposited at Harvard’s Houghton Library in 1934, contains a manuscript note claiming that the book was bound in skin taken from the back of a woman, since “a book about the human soul deserved to have a human covering.” Researchers confirmed the claim using several techniques, including peptide mass fingerprinting (PMF), which identifies proteins.
“The PMF from ‘Des destinées de l’ame’ matched the human reference, and clearly eliminated other common parchment sources, such as sheep, cattle and goat,” Bill Lane, the director of the Harvard Mass Spectrometry and Proteomics Resource Laboratory, and Daniel Kirby, of the Straus Center for Conservation and Technical Studies, told the Houghton Library Blog.
That test could not rule out the possibility that the book was bound in the skin of a great ape or a gibbon. But researchers said that additional scientific analysis, along with information about the book’s provenance, made that extremely unlikely.
The practice of binding books in human skin, which dates at least to the 16th century, was once somewhat common, according to the Houghton blog. Criminal confessions were occasionally bound in the skin of the convicted, and individuals might request to be memorialized for family or lovers in the form of a book covered in a piece of themselves.

If that practice seems grisly today, the more ordinary practice of binding books in animal skins has been problematic in some places, according to Leah Price, an English professor and book historian at Harvard who was not involved in the analysis.
“In 19th-century India, some Christian missionaries made the mistake of trying to distribute bibles bound in calfskin or containing pig byproducts,” Ms. Price said by email. “It’s not just about the binding: until the 20th century most glues used in books as well as the ‘sizing’ used to coat paper were made by boiling down pieces of animal carcass.”

 

Nakupa Habari: Truvada, a breakthrough in HIV prevention

Nakupa Habari: Truvada, a breakthrough in HIV prevention: Truvada, a breakthrough in HIV prevention.   Truvada drug has emerged as a new warrior in the battle against AIDS and HIV, however the...

Truvada, a breakthrough in HIV prevention

Truvada, a breakthrough in HIV prevention.

 

Truvada drug has emerged as a new warrior in the battle against AIDS and HIV, however the drug's acceptation among the public in the fight against HIV and AIDS has been slow.

The drug was approved in 2000s for the treatment of affected patients, and it works by slowing the progression of the disease and reducing the amount of deadly virus in the human body.
In July 2012, Truvada was approved for Pre-exposure prophylaxis. The use was meant for those people, who might be at risk of contracting HIV virus, used as a preventive measure.

U.S. Centers for Disease Control and Prevention (CDC) released guidelines this year in May about who can take Truvada. The recommendations involved half a million people, which is seen as a significant increase from the 2000 people, who are already taking the drugs at the moment.

In spite of Truvada's approval as a precautionary measure, many healthcare providers have been reluctant in accepting it. Moreover, there have been some backlashes from gay communities as well.

There have been some misunderstandings on how Truvada should be used that have led to unacceptable by healthcare providers. However, there are clear guidelines recommended by CDC about who should use the medicine.

 According to Michael Weinstein, who is the president of AIDS Healthcare Foundation, the drug should be taken daily but it is not certain whether people will take the drug every day.
Missing the pill or not taking it every day actually reduces the overall effectiveness of the drug. Moreover, Truvada does not protect against other sexually transmitted diseases (STD), therefore using the medicine to prevent AIDS might lead to assumption that there is no need to use condoms, which can encourage the occurrence of other diseases as well.

The drug requires a preliminary HIV test along with follow-up tests every 3 months for STD and HIV infections. There will be tests for organ damage owing to drug toxicity as well. Truvada costs almost 13,000 dollars a year, which is expensive, though several insurers cover it.

 

Thursday, 5 June 2014

Nakupa Habari: Pollution link to irregular heartbeat and lung clo...

Nakupa Habari: Pollution link to irregular heartbeat and lung clo...:   Particulate matter in air pollution can have an adverse effect on heart health.   Air pollution is linked to increased risk of dev...

Pollution link to irregular heartbeat and lung clotting.

car exhaust 

Particulate matter in air pollution can have an adverse effect on heart health.

  Air pollution is linked to increased risk of developing an irregular heartbeat and blood clots in the lung, research suggests.

The impact of air pollution on the risk of heart attack and stroke is less clear, say UK experts.
Analysis of data from England and Wales shows air pollution is particularly harmful in the elderly.
Further research is needed on pollution and cardiovascular health, says the British Heart Foundation.
A team at the London School of Hygiene & Tropical Medicine analyzed data collected in England and Wales between 2003 and 2009 on links between cardiovascular problems and short-term air pollution.
They found short-term air pollution was linked to arrhythmia (abnormal heart rhythm) and blood clots in the lung.

The strongest link was in the over-75s and in women, lead researcher Dr Ai Milojevic told BBC News.
"Our main message is that we didn't have clear evidence for air pollution impact on stroke or heart attack, which ultimately represent general blood clotting processes," she said.
Bigger picture
Commenting on the study, published in the journal, Heart, the British Heart Foundation said previous studies had shown air pollution could make existing heart and circulatory conditions, including heart attacks, worse in vulnerable people.
"This research adds weight to what we already know, but goes further to suggest a link between air pollution and an increased risk of blood clots in the lungs and heart rhythm atrial fibrillation," said Julie Ward, senior cardiac nurse.
"But, as with many studies, we do need to look at the bigger picture and, although this is a large comprehensive study, it did have its limitations.
"We do, therefore, recognise that further research into exactly how air pollution particles affect the cardiovascular system needs to be carried out."

Seven million people died as a result of air pollution in 2012, according to World Health Organization estimates.
Its findings suggest a link between air pollution and heart disease, respiratory problems and cancer.

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